Coenzyme Q10 40% Water-dispersive Powder-E (40SPE)
Characteristics
- "40SPE" is a raw material for foods that is processed from water-insoluble coenzyme Q10 to a water-dispersive powder by introduction of a leading emulsifying and powder-producing technology.
- "40SPE" is extremely easy to disperse into water.
- Non-hygroscopic type
Specifications
| Items to test | Specification | Test method |
|---|---|---|
| Appearance | Yellow to orange | Visual inspection |
| Content of Coenzyme Q10* | NLT 40.0% | HPLC method |
| Heavy metal | NMT 10μg/g | Food Sanitation Law(JP) |
| Number of live bacteria | NMT 300cfu/g | Standard Methods of Analysis in Food Safety Regulations(JP) |
| Total Coliforms | Negative | Standard Methods of Analysis in Food safety Regulations(JP) |
*; Based on Kaneka Coenzyme Q10
Use application
For tablet, capsule, granule and other general foods.
Fully complied with EU food regulation.
The bioavailability of Water-dispersive Powder
(40SPE) after single oral administration
In this study, we showed the bioavailability of Coenzyme Q10 40% Water-dispersive Powder-E (40SPE). 4 healthy subjects received single oral administration of 100mg of Q10 in the form of a soft capsule※ containing Q10 dissolved in Olive oil, a 40SPE in a hard capsule and a 40SPE mixed with Olive oil in a hard capsule in the fasting period, and changes in the plasma ubiquinol concentration were monitored over time. AUC0-24hr values were 2.99, 8.00 and 8.82μgh/ml, respectively. 4 healthy subjects did not take any coenzyme supplements or drinks for 3 weeks, and did not take anything but water from 6:00 p.m. on the day before to 6:00 p.m. on the day of trial. The same 4 subjects repeated the trial in the same manner.
※Ingredients of commercial soft capsule：CoQ10, Olive oil, glycerin, lecithin, vitamin E, etc.
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